Formulation Comparison

Comparing Various Tobramycin Inhalation Solutions

  • Kitabis™ Pak1
    Tobramycin Inhalation Solution

    Contents:
    56 vials of tobramycin inhalation solution.

    One PARI LC PLUS® Reusable Nebulizer with tubing & Instructions.
    Indication:
    Management of cystic fibrosis patients with Pseudomonas aeruginosa.

    Safety and efficacy have not been demonstrated in patients under the age of 6 years, patients with FEV1 <25% or >75% predicted, or patients colonized with Burkholderia cepacia.
    Volume:
    5 mL
    Dosage:
    300 mg
    Treatment Time:
    Approximately 15 minutes
    Dosing:
    One single-use ampule (300 mg/5ml) of tobramycin inhalation solution twice a day by oral inhalation in repeated cycles of 28 days on drug, followed by 28 days off drug.
    Concentration:
    60 mg/mL
    Nebulizer/Compressor:
    PARI LC PLUS® Reusable Nebulizer with a DeVilbiss Pulmo-Aide® air compressor.
    Nebulizer Co-Pay, Co-Insurance or Deductible:
    NO
    Storage:
    Under refrigeration at 36°-46°F/2°-8°C. May be stored at room temperature for up to 28 days
    Contents
    Indication
    Volume
    Dosage
    Treatment Time
    Dosing
    Concentration
    Nebulizer/Compressor
    Nebulizer Co-Pay, Co-Insurance or Deductible
    Storage
  • Bethkis®2
    Tobramycin Inhalation Solution

    Contents:
    56 vials of tobramycin inhalation solution.
    Indication:
    Management of cystic fibrosis patients with Pseudomonas aeruginosa.

    Safety and efficacy have not been demonstrated in patients under the age of 6 years, patients with FEV1 <40% or >80% predicted, or patients colonized with Burkholderia cepacia.
    Volume:
    4 mL
    Dosage:
    300 mg
    Treatment Time:
    Approximately 15 minutes
    Dosing:
    One single-use ampule (300mg/4ml) of tobramycin inhalation solution twice a day by oral inhalation in repeated cycles of 28 days on drug followed by 28 days off drug.
    Concentration:
    75 mg/mL
    Nebulizer/Compressor:
    PARI LC PLUS® Reusable Nebulizer with a PARI Vios® air compressor.
    Nebulizer Co-Pay, Co-Insurance or Deductible:
    YES
    Storage:
    Under refrigeration at 36°-46°F/2°-8°C. May be stored at room temperature for up to 28 days.
  • Tobi®3
    Tobramycin Inhalation Solution

    Contents:
    56 vials of tobramycin inhalation solution
    Indication:
    Management of cystic fibrosis patients with Pseudomonas aeruginosa.

    Safety and efficacy have not been demonstrated in patients under the age of 6 years, patients with FEV1 <25% or >75% predicted, or patients colonized with Burkholderia cepacia.
    Volume:
    5 mL
    Dosage:
    300 mg
    Treatment Time:
    Approximately 15 minutes
    Dosing:
    One single-use ampule (300mg/5ml) of tobramycin inhalation solution twice a day by oral inhalation in repeated cycles of 28 days on drug followed by 28 days off drug.
    Concentration:
    60 mg/mL
    Nebulizer/Compressor:
    PARI LC PLUS® Reusable Nebulizer with a DeVilbiss Pulmo-Aide® air compressor.
    Nebulizer Co-Pay, Co-Insurance or Deductible:
    YES
    Storage:
    Under refrigeration at 36°-46°F/2°-8°C. May be stored at room temperature for up to 28 days
*Trademarks are the property of their respective companies.

1 Kitabis Pak [package insert]. Midlothian, VA: PARI Respiratory Equipment, Inc; 2014.
2 BETHKIS [package insert]. Cary, NC: Cornerstone Therapeutics Inc; 2013.
3 TOBI [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2014.